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apalutamide will lessen the extent or effect of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with drugs which have been CYP3A4 substrates can lead to lessen exposure to those remedies.Amid these kinds of populations, about